Venous

	venous
	Disorders affecting how the blood circulates through the veins, including varicose veins, spider veins, thrombosis. "Klinefelter syndrome predisposes patients to various venous diseases. In 1 study, 21 (20%) of 104 patients had varicose veins, which were often severe and appeared at an early age.²⁴ There is a 10- to 20-fold increased prevalence of venous ulcers and an increased risk for deep venous thrombosis and pulmonary embolism, perhaps related to a basement membrane defect in venous valves or an underlying hypercoagulable state."^10,60-61 From: "Klinefelter Syndrome" Cynthia M. Smyth, MD; William J. Bremner, MD, PhD Arch Intern Med. 1998;158:1309-1314 10. King RA, Potter JI, Motulsky AH. The Genetic Basis of Common Disease. New York, NY: Oxford University Press; 1992:876-894. 24. Becker KL. Clinical and therapeutic experiences with Klinefelter's syndrome. Fertil Steril. 1972;23:568-578. 60. Campbell WA, Newton MS, Price WH. Hypostatic leg ulceration and Klinefelter's syndrome. J Ment Defic Res. 1980;24:115-117. 61. Campbell WA, Price WH. Venous thromboembolic disease in Klinefelter's syndrome. Clin Genet. 1981;19:275-280 Vascular Disease Foundation Back Top This page first created: May 24, 2000

venous

Disorders affecting how the blood circulates through the veins, including varicose veins, spider veins, thrombosis.

"Klinefelter syndrome predisposes patients to various venous diseases. In 1 study, 21 (20%) of 104 patients had varicose veins, which were often severe and appeared at an early age.²⁴ There is a 10- to 20-fold increased prevalence of venous ulcers and an increased risk for deep venous thrombosis and pulmonary embolism, perhaps related to a basement membrane defect in venous valves or an underlying hypercoagulable state."^10,60-61

From:
"Klinefelter Syndrome"
Cynthia M. Smyth, MD; William J. Bremner, MD, PhD
Arch Intern Med. 1998;158:1309-1314

10. King RA, Potter JI, Motulsky AH. The Genetic Basis of Common Disease. New York, NY: Oxford University Press; 1992:876-894.
24. Becker KL. Clinical and therapeutic experiences with Klinefelter's syndrome. Fertil Steril. 1972;23:568-578.
60. Campbell WA, Newton MS, Price WH. Hypostatic leg ulceration and Klinefelter's syndrome. J Ment Defic Res. 1980;24:115-117.
61. Campbell WA, Price WH. Venous thromboembolic disease in Klinefelter's syndrome. Clin Genet. 1981;19:275-280

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This page first created: May 24, 2000